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(343) 333-44-33
г. Екатеринбург, 22-го Партсъезда, 50
Генотипы и мутации, приводящие к резистентности к изониазиду (INH), рифампицину (RIF), аминогликозидам (AG) и фторхинолонам (FQ), у клинических изолятов Mycobacterium tuberculosis Mycobacterium tuberculosis clinical isolates' genotypes and mutations, conferring resistance to antituberculosis drugs  (изоляты от ВИЧбольных / isolated from HIV-patients)
  Лабораторный номер / Laboratory № Мутации, связанные с резистентностью к: / Mutations conferring resistance to:
RIF INH   EMB FQ  AG Генотип / Genotype
rpoB katG, inhA ahpC
embB gyrA  gyrB      eis rrs
1 A0020-20 wt wt wt wt wt wt wt wt wt T 1_RUS  2
2 A0022-20 Asp516Tyr Ser315Thr wt wt wt wt wt wt wt Beijing
3 A0031-20 wt wt wt wt wt wt wt wt wt T 2
4 A0041-20 wt wt wt wt wt wt wt wt wt LAM
5 A0046-20 wt wt wt wt wt wt wt wt wt не опр/not ident.
6 A0048-20 wt Ser315Thr wt wt wt wt wt wt wt Beijing
7 A0064-20 Ser531Leu Ser315Thr wt wt Gln497Lys Ala90Gly-Ser91Pro wt wt wt B0 / W148 Beijing
8 A0070-20 wt wt T8A wt wt wt wt wt wt Beijing
9 A0073-20 Ser531Leu Ser315Thr wt wt Met306Leu wt wt wt wt Beijing
10 A0076-20 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt Gly10Ala wt B0 / W148 Beijing
11 A0077-20 Leu533Pro Ser315Thr wt wt Gly406Ala wt wt Gly10Ala wt B0 / W148 Beijing
12 A0078-20 Ser531Leu Ser315Thr wt wt Met306Val wt wt Cys14Thr wt B0 / W148 Beijing
13 A0082-20 wt wt wt wt wt wt wt wt wt Beijing
14 A0089-20 wt wt wt wt wt wt wt wt wt Ural
15 A0091-20 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt wt wt Beijing
16 A0092-20 Ser531Leu Ser315Thr wt wt Met306Leu Asp94HisSer95Thr wt Cys12Thr wt Beijing
17 A0093-20 wt wt wt wt wt wt wt wt wt Beijing
18 A0094-20 wt Ser315Thr wt wt Met306Leu wt wt Cys12Thr wt B0 / W148 Beijing
19 A0095-20 Asp516Tyr Ser315Thr wt wt Val309Phe Asp94AsnSer95Thr wt wt Ala1401Gly Beijing
20 A0104-20 wt wt wt wt wt wt wt wt wt Beijing
21 A0108-20 Ser531Leu Ser315Thr wt wt Gln497Lys Ala90Gly-Ser91Pro wt Gly10Ala wt B0 / W148 Beijing
22 A0111-20 Ser531Leu Ser315Thr wt wt Met306Val Ala90Gly-Ser91Pro wt wt wt B0 / W148 Beijing
23 A0115-20 Ser531Leu Ser315Thr wt wt Met306Leu wt wt wt Ala1401Gly Beijing
24 A0116-20 wt wt wt wt wt wt wt wt wt Ural
25 A0117-20 wt wt wt wt wt wt wt wt wt Beijing
26 A0118-20 wt wt T8A wt wt wt wt wt wt Beijing
27 A0123-20 wt wt wt wt Asn296His wt wt wt wt Ural
28 A0125-20 Ser531Leu Ser315Thr wt wt Met306Val wt wt  Gly37Thr wt LAM
29 A0129-20 wt Ser315Thr wt wt Met306Leu wt wt wt wt B0 / W148 Beijing
30 A0130-20 wt wt wt wt wt wt wt wt wt X 1
31 A0134-20 Ser531Leu Ser315Thr wt wt Met306Leu wt wt wt wt Beijing
32 A0136-20 Ser531Leu Ser315Thr wt wt Met306Leu wt wt wt Ala1401Gly Beijing
33 A0144-20 Ser531Leu Ser315Thr wt wt Met306Val wt wt  Gly37Thr wt LAM
34 A0157-20 Ser531Leu wt wt wt wt wt wt wt wt Haarlem
35 A0158-20 wt wt wt wt wt wt wt wt wt T 4
36 A0161-20 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
37 A0171-20 Ser531Leu Ser315Thr wt wt Gln497Lys wt wt wt wt B0 / W148 Beijing
38 A0220-20 Ser531Leu wt wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
39 A0327-20 Ser531Leu wt wt wt Met306Val wt wt wt wt B0 / W148 Beijing
40 A0728-20 wt Ser315Thr wt wt Met306Val wt wt Cys14Thr wt B0 / W148 Beijing
41 A0730-20 wt wt wt wt wt wt wt wt wt Ural
42 A0734-20 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt wt Ala1401Gly B0 / W148 Beijing
43 A0738-20 Ser531Leu Ser315Thr wt wt wt Pro102His wt wt wt B0 / W148 Beijing
44 A0740-19 wt Ser315Thr wt wt wt wt wt wt wt Beijing
45 A0761-19 wt wt wt wt wt wt wt wt wt Beijing
46 A0831-19 wt wt  T15A wt Gly406Ala wt wt wt wt B0 / W148 Beijing
47 A0882-19 Leu511Pro Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
48 A0883-19 wt wt wt wt Asn296His wt wt wt wt B0 / W148 Beijing
49 A0885-20 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
50 A0887-19 wt Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
51 A0888-19 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
52 A0890-19 Ser531Leu Ser315Thr wt wt Gly406Ala Asp94AsnSer95Thr wt wt Ala1401Gly B0 / W148 Beijing
53 A0891-20 Ser531Leu wt wt wt Asn296His wt wt wt wt B0 / W148 Beijing
54 A0894-20 wt Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
55 A0895-20 Ser531Leu Ser315Thr  T15A wt Gln497Arg wt wt wt wt Beijing
56 A1052-19 Ser531Leu Ser315Thr wt wt Gly406Ala Ala90Gly-Ser91Pro wt Gly10Ala wt B0 / W148 Beijing
57 A1053-19 wt wt  T15A wt wt wt wt wt wt B0 / W148 Beijing
58 A1054-19 Ser531Leu Ser315Thr wt wt Gly406Ala Asp94AsnSer95Thr wt wt wt B0 / W148 Beijing
59 A1055-19 Ser531Leu Ser315Thr wt wt Gly406Ala   wt Ala1401Gly wt B0 / W148 Beijing
60 A1056-19 wt wt wt wt Met306Leu   wt wt wt B0 / W148 Beijing
61 A1057-19 Ser531Leu Ser315Thr wt wt Val309Phe Asp94AsnSer95Thr wt Cys12Thr wt B0 / W148 Beijing
62 A1058-19 Asp516Tyr wt wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
63 A1059-19 His526Asn Ser315Thr wt wt wt wt wt wt wt LAM
64 A1060-19 wt Ser315Thr  T15A wt Gly406Ala wt wt wt wt B0 / W148 Beijing
65 A1135-19 Ser531Leu Ser315Thr wt wt Gly406Ala wt Ser486Phe wt Ala1401Gly B0 / W148 Beijing
66 A1147-19 Ser531Leu wt wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
67 A1260-19 Ser531Leu Ser315Thr wt wt Gly406Ala Asp94AsnSer95Thr wt Ala1401Gly wt B0 / W148 Beijing
68 A1269-19 wt Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
69 A1271-19 wt Ser315Thr wt wt wt wt wt wt wt B0 / W148 Beijing
70 A1455-19 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
71 A1457-19 wt wt wt wt wt wt wt wt wt Beijing
72 A1459-19 Ser531Leu Ser315Thr wt wt Met306Val Asp94GlySer95Thr wt Gly10Ala wt Beijing
73 A1480-19 wt wt wt wt Met306Val wt wt wt wt Beijing
74 A1483-19 wt wt wt wt Met306Leu wt wt wt wt B0 / W148 Beijing
75 A1484-19 Ser531Leu Ser315Thr wt wt Met306Val wt wt wt Ala1401Gly Beijing
76 A1485-19 Ser531Leu Ser315Thr wt wt Met306Val wt wt wt wt Beijing
77 A1588-19 Ser531Leu Iley335Val wt wt Asn296His wt wt Gly10Ala wt Beijing
78 A1599-19 wt Ser315Thr wt wt Asn296His wt wt wt wt B0 / W148 Beijing
79 A1746-19 wt wt wt wt wt wt wt wt wt Beijing
80 A1747-19 Ser531Leu Ser315Thr wt wt Met306Val Asp94GlySer95Thr wt wt wt Beijing
81 A1748-19 Ser531Leu Ser315Thr wt wt wt wt wt wt wt Beijing
82 A1749-19 His526Asn wt wt wt wt wt wt wt wt LAM
83 A1752-19 Ser531Leu wt wt wt wt wt wt wt wt Beijing
84 A1873-19 Ser531Leu Ser315Thr wt wt Asn296His Asp94GlySer95Thr wt wt wt Beijing
85 A1878-19 Ser531Leu Ser315Thr wt wt wt wt Asn538 Asp wt wt Beijing
86 A1881-19 Ser531Leu wt wt wt wt wt wt wt wt Beijing
87 A1887-19 Leu511Pro Ser315Thr wt wt Asn296His Asp94GlySer95Thr wt Gly10Ala wt Beijing
88 A2056-19 wt wt wt wt wt wt wt wt wt Beijing
89 A2057-19 Ser531Leu Ser315Thr wt wt Met306Val wt wt wt Ala1401Gly Beijing
90 A2060-19 Ser531Leu Iley335Val wt wt wt wt wt Gly10Ala wt Beijing
91 A2065-19 wt wt T8A wt wt wt wt wt wt Beijing
92 A2092-19 Ser531Leu Ser315Thr wt wt wt wt wt wt wt Beijing
93 A2171-19 Ser531Leu wt wt wt Met306Val wt wt wt wt Beijing
94 A2197-19 Ser531Leu Ser315Thr wt wt Asn296His wt wt Gly10Ala wt Beijing
95 A2199-19 wt wt  T15A wt wt wt wt wt wt LAM
96 A2201-19 wt wt wt wt wt wt wt wt wt LAM
97 A2202-19 wt wt wt wt wt wt wt wt wt Beijing
98 A2203-19 Leu511Pro Ser315Thr wt wt Met306Val wt wt Gly10Ala wt Beijing
99 A2379-19 Ser531Leu Ser315Thr wt wt wt wt wt wt wt Beijing
100 A2380-19 wt wt wt wt wt wt wt wt wt Beijing
101 A2381-19 Ser531Leu wt wt wt Asn296His wt wt wt wt Beijing
102 A2382-19 wt wt wt wt wt wt wt wt wt LAM
103 A2385-19 Ser531Leu Ser315Thr wt wt wt Asp94GlySer95Thr wt wt Ala1401Gly Beijing
104 A2386-19 Ser531Leu wt wt wt Met306Val wt wt wt wt Beijing
105 A2387-19 Ser531Leu Ser315Thr wt wt wt wt wt Gly10Ala wt Beijing
106 A2562-19 wt wt wt Cys12Thr wt wt wt wt wt Ural
107 A2564-19 wt wt wt wt wt wt wt wt wt Beijing
108 A2565-19 Ser531Leu Ser315Thr wt wt Tyr319Ser wt wt wt wt Beijing
109 A2567-19 wt wt wt wt wt wt wt wt wt Beijing
110 A2568-19 Ser531Leu wt wt wt Asn296His wt wt wt wt Beijing
111 A2570-19 wt wt wt wt wt wt wt wt wt LAM
112 A2571-19 wt wt wt wt wt wt wt wt wt Beijing
113 A2738-19 Ser531Leu Ser315Thr wt wt wt wt wt wt Ala1401Gly Beijing
114 A2752-19 Ser531Leu Ser315Thr wt wt wt Asp94GlySer95Thr wt Gly10Ala wt Beijing
115 A2753-19 wt wt wt wt wt wt wt wt wt Beijing
116 A2754-19 wt wt wt wt wt wt wt wt wt Beijing
117 A2792-19 Ser531Leu Ser315Thr wt wt wt wt wt wt wt Beijing
118 A2794-19  wt wt wt wt wt wt wt wt wt Beijing
119 A2795-19 Ser531Leu wt wt wt Met306Leu wt wt wt wt Beijing
120 A2796-19 Ser531Leu Ser315Thr wt wt wt wt wt wt Ala1401Gly Beijing
121 A2799-19 Ser531Leu Ser315Thr wt wt wt Asp94GlySer95Thr wt wt wt Beijing
122 A2800-19 wt wt wt wt wt wt wt wt wt LAM
123 A2804-19 wt wt wt wt wt wt wt wt wt Beijing
124 A2817-19 Ser531Leu Ser315Thr wt wt wt wt wt wt wt Beijing
125 A2820-19 Ser531Leu Ser315Thr wt wt wt Asp94GlySer95Thr wt wt Ala1401Gly Beijing
126 A2945-19 wt wt wt wt wt wt wt wt   Beijing
127 A2947-19 wt Ser315Thr wt wt wt wt wt wt Ala1401Gly Beijing
128 A2949-19 Ser531Leu Ser315Thr wt wt wt wt wt wt wt Beijing
129 A2950-19 wt wt wt wt wt wt wt wt wt Beijing
130 A2951-19 Asp516Tyr Ser315Thr wt wt wt wt wt wt wt Beijing
131 A2953-19 Ser531Leu Ser315Thr wt wt wt wt wt wt Ala1401Gly Beijing
132 A2976-19 Ser531Leu Ser315Thr wt wt wt Asp94GlySer95Thr wt Gly10Ala wt Beijing
133 A2977-19 wt wt wt wt wt wt wt wt wt Ural
134 A2978-19 wt wt wt wt wt wt wt wt wt Beijing
135 A3185-19 Ser531Leu Ser315Thr wt wt Gln497Lys Ala90Gly-Ser91Pro wt  Gly37Thr wt B0 / W148 Beijing
136 A3186-19 His526Asn Ser315Thr wt wt Asp354Ala wt wt  Gly37Thr wt LAM
137 A3190-19 wt wt wt wt wt wt wt wt wt Beijing
138 A3192-19 Ser531Leu Ser315Thr wt wt Asp354Ala Asp94AlaSer95Thr wt wt wt LAM
139 A3228-19 Asp516Tyr Ser315Thr wt wt wt wt wt wt wt Beijing
140 A3229-19 Ser531Leu Ser315Thr wt wt Tyr319Ser Asp94HisSer95Thr wt wt Ala1401Gly Beijing
141 A3417-19 Ser531Leu Ser315Thr wt wt wt Asp94AsnSer95Thr wt wt wt Beijing
142 A3444-19 wt wt wt wt wt wt wt wt wt Beijing
143 A3445-19 wt wt wt wt wt wt wt wt wt Beijing
144 A3447-19 wt wt wt wt wt wt wt wt wt Beijing
145 A3448-19 Ser531Leu Ser315Thr wt wt wt Asp94AsnSer95Thr wt wt wt Beijing
146 A3449-19 wt wt wt wt wt wt wt wt wt Beijing
147 A3458-19 Ser531Leu Ser315Thr wt wt wt Asp94AsnSer95Thr wt Cys12Thr wt Beijing
148 A3459-19 wt wt wt wt wt wt wt wt wt Beijing
149 A3460-19 wt wt  T15A wt wt wt wt wt wt LAM
150 A3493-19 wt wt wt wt wt wt wt wt wt Beijing
151 A3494-19 His526Tyr wt wt wt wt wt wt wt wt Beijing
152 A3495-19 wt wt wt wt wt wt wt wt wt Beijing
153 A3496-19 wt wt wt wt wt wt wt wt wt Beijing
154 A3497-19 wt wt wt wt wt wt wt wt wt Beijing
155 A3499-19 Ser531Leu Ser315Thr wt wt wt wt wt Gly10Ala wt Beijing
156 A3686-19 wt wt wt wt wt wt wt wt wt Beijing
157 A3688-19 Asp516Tyr Ser315Thr wt wt wt wt wt wt wt Beijing
158 A3694-19 wt wt wt wt wt wt wt wt wt Beijing
159 A3696-19 wt wt wt wt wt wt wt wt wt Beijing
160 A3700-19 Ser531Leu Ser315Thr wt wt  Tyr319Cys Asp94AsnSer95Thr wt Cys14Thr wt LAM
161 A3895-19 wt Ser315Thr wt wt wt wt wt wt wt Beijing
162 A3896-19 wt wt wt wt wt wt wt wt wt LAM
163 A3897-19 Ser531Leu Ser315Thr wt wt Met306Leu wt wt wt wt Beijing
164 A4361-19 wt Ser315Thr wt wt wt wt wt wt wt LAM
165 A4433-19 wt wt wt wt wt wt wt wt wt LAM
166 A4512-19 wt wt wt wt Asn296His wt wt wt wt Ural
167 A4514-19 wt wt wt wt wt wt wt wt wt LAM
168 A4518-19 wt wt wt wt wt wt wt wt wt Ural
169 A4520-19 wt wt wt wt wt wt wt wt wt Ural
170 A4523-19 wt wt wt wt wt wt wt wt wt LAM
171 A4535-19 wt wt  T15A wt wt wt wt wt wt LAM
172 A4537-19 wt wt wt wt wt wt wt wt wt Beijing
173 A4592-19 Ser531Leu Ser315Thr T15 wt Met306Leu wt wt wt wt Beijing
174 A4650-19 wt wt wt wt wt wt wt wt wt Beijing
175 A4680-19 wt wt wt wt wt wt wt wt wt Ural
176 A4681-19 wt wt wt wt wt wt wt wt wt Ural
177 A4707-19 wt Ser315Thr wt wt Val309Phe wt wt  Gly37Thr wt LAM
178 A4805-19 Ser531Leu Ser315Thr T15 wt Val309Phe wt wt wt wt Beijing
179 A4809-19 Ser531Leu Ser315Thr wt wt Met306Leu wt wt wt wt Beijing
180 A4861-19 wt wt wt wt wt wt wt wt wt LAM
181 A4905-19 wt wt T8A wt wt wt wt wt wt Beijing
182 A4927-19 wt wt wt wt wt wt wt wt wt LAM
183 A4972-19 Ser531Leu Ser315Thr wt wt Met306Val Pro102His wt  Gly37Thr wt LAM
184 A5010-19 wt wt wt wt wt wt wt wt wt LAM 1
185 A5048-19 wt wt wt wt wt wt wt wt wt LAM
186 A5192-19 wt wt wt wt wt wt wt wt wt Beijing
187 A5196-19 wt Ser315Thr wt wt wt wt wt wt wt LAM
188 A5197-19 wt wt wt wt wt wt wt wt wt Ural
189 A5202-19 wt wt  T15A wt wt wt wt wt wt LAM
190 A5213-19 wt wt wt wt wt wt wt wt wt X 1
191 A5237-19 wt Ser315Thr wt wt Val309Phe wt wt wt wt не опр./ not ident.
192 A5294-19 Ser531Leu Ser315Thr T15 wt Val309Phe wt wt wt wt Beijing
193 A5295-19 wt wt wt wt wt wt wt wt wt Beijing
194 A5300-19 Ser531Leu Ser315Thr wt wt Gly406Ala Asp94AlaSer95Thr wt wt wt B0 / W148 Beijing
195 A5358-19 wt wt wt wt wt wt wt wt wt LAM
196 A5361-19 wt wt wt wt wt wt wt wt wt LAM
197 A5363-19 wt wt wt wt wt wt wt wt wt Ural
198 A5364-19 Ser531Leu Ser315Thr wt wt Gln497Lys Ala90Gly-Ser91Pro wt wt wt B0 / W148 Beijing
199 A5463-19 Ser531Leu Ser315Thr wt wt Met306Leu Asp94GlySer95Thr wt wt wt LAM
200 A5475-19  wt wt wt wt wt wt wt wt wt LAM
201 A5476-19 Ser531Leu Ser315Thr wt wt Met306Val   wt wt wt B0 / W148 Beijing
202 A5536-19 Ser531Leu Ser315Thr wt wt Gly406Ala Asp94AlaSer95Thr wt  Gly37Thr wt B0 / W148 Beijing
203 A5597-19 wt wt  T15A wt wt wt wt wt wt LAM
204 A5607-19 Ser531Leu Ser315Thr wt wt Met306Val wt wt  Gly37Thr wt LAM
205 A5639-19 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
206 A5644-19 wt wt wt wt wt wt wt wt wt Haarlem
207 A5703-19 Ser531Leu Ser315Thr wt wt Gly406Ala Asp94AlaSer95Thr wt wt wt B0 / W148 Beijing
208 A5704-19 wt wt wt wt wt wt wt wt wt EAL
209 A5715-19 wt wt T8A wt wt wt wt wt wt Beijing
210 A5721-19 wt wt wt wt wt wt wt wt wt Ural
211 A5722-19 wt wt wt wt wt wt wt wt wt LAM
212 A5723-19 wt wt wt wt wt wt wt wt wt LAM
213 A5745-19 wt wt wt wt wt wt wt wt wt T 1
214 A5747-19 wt wt wt wt wt wt wt wt wt Ural
215 A5756-19 wt wt wt wt wt wt wt wt wt Ural
216 A5780-19 wt wt  T15A wt wt wt wt wt wt LAM
217 A5809-19 wt wt wt wt wt wt wt wt wt T1
218 A5866-19 wt wt wt wt wt wt wt wt wt T 1
219 A5933-19 wt wt wt wt wt wt wt wt wt Ural
220 A5936-19 wt wt wt wt wt wt wt wt wt LAM
221 A5989-19 Leu533Pro Ser315Thr wt wt Gly406Ala Ala90Gly-Ser91Pro wt wt wt B0 / W148 Beijing
222 A6000-19 wt wt wt wt wt wt wt wt wt Beijing
223 A6003-19 wt wt wt wt wt wt wt wt wt T 3
224 A6070-19 wt Ser315Thr wt wt Asn296His wt wt Cys14Thr wt Ural
225 A6071-19-19 Ser531Leu Ser315Thr wt wt Val309Phe Pro102His wt wt Ala1401Gly Beijing
226 A6076-19 wt wt wt wt wt wt wt wt wt Beijing
227 A6133-19 Ser531Leu Ser315Thr wt wt Gly406Ala   wt wt wt B0 / W148 Beijing
228 A6136-19 wt wt wt wt wt wt wt wt wt LAM
229 A6138-19 wt wt wt wt wt wt wt wt wt Beijing
230 A6139-19 wt wt wt wt wt wt wt wt wt LAM
231 A6205-19 wt   wt wt wt wt wt Gly10Ala wt LAM
232 A6212-19 wt wt wt wt wt wt wt wt wt T 3
233 A6284-19 Ser531Leu wt wt wt wt wt wt wt wt Beijing
234 A6287-19 wt wt T8A wt wt wt wt wt wt Beijing
235 A6333-19 wt wt wt wt wt wt wt wt wt EAL
236 A6337-19 Ser531Leu Ser315Thr wt wt Gly406Ala Asp94AlaSer95Thr wt wt wt B0 / W148 Beijing
237 A6339-19 wt wt wt wt wt wt wt wt wt Beijing
238 A6486-19 Ser531Leu Ser315Thr wt wt wt wt wt wt wt Beijing
239 A6553-19 wt wt wt wt wt wt wt wt wt LAM
240 A6562-19 wt wt wt wt wt wt wt wt wt Beijing
241 A6566-19 Ser531Leu Ser315Thr wt wt wt Asp94AsnSer95Thr wt wt Ala1401Gly Beijing
242 A6607-19 Ser531Leu Ser315Thr wt wt wt Asp94GlySer95Thr wt  Gly37Thr wt LAM
243 A6638-19 wt wt wt wt wt wt wt wt wt LAM
244 A6694-19 Ser531Leu Ser315Thr wt wt Met306Leu Asp94TyrSer95Thr wt wt Ala1401Gly Beijing
245 A6797-19 Ser531Leu Ser315Thr wt wt Met306Leu wt wt wt Ala1401Gly Beijing
246 A6812-19 wt Ser315Thr wt wt Met306Val wt wt wt wt T 1_RUS 2
247 A6899-19 wt   wt wt wt wt wt wt wt T 1
248 A6923-19 His526Leu wt wt wt Met306Leu wt wt wt wt Beijing
249 A6925-19 wt wt wt wt wt wt wt wt wt Ural
250 A6927-19 wt wt wt wt wt wt wt wt wt Ural
251 A6928-19 wt wt T8A wt wt wt wt wt wt Beijing
252 A6929-19 Leu533Pro Ser315Thr wt wt Gly406Ala Asp94AlaSer95Thr wt wt wt B0 / W148 Beijing
253 A6999-19 wt wt wt wt wt wt wt wt wt Ural
254 A7000-19 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt Gly10Ala wt B0 / W148 Beijing
255 A7029-19 wt wt wt wt wt wt wt wt wt T 1
256 A7057-19 wt wt wt wt wt wt wt wt wt X 1
257 A7073-19 wt wt wt wt wt wt wt wt wt LAM
258 A7101-19 wt wt wt wt wt wt wt wt wt Ural
259 A7138-19 wt wt wt wt wt wt wt wt wt Ural
260 A7231-19 wt wt  T15A wt wt wt wt wt wt LAM
261 A7235-19 wt wt wt wt wt wt wt wt wt Ural
262 A7236-19  Asp516Val Ser315Thr wt wt Met306Val wt wt  Gly37Thr wt LAM
263 A7240-19 wt wt wt wt wt wt wt wt wt Ural
264 A7251-19 wt wt wt wt wt wt wt wt wt LAM
265 A7407-19 wt wt wt wt wt wt wt wt wt Beijing
266 A7484-19 wt wt wt wt wt wt wt wt wt LAM
267 A7559-19 wt wt T8A wt wt wt wt wt wt Beijing
268 A7560-19 wt wt wt wt wt wt wt wt wt Beijing
269 A7568-19 Ser512Thr Ser315Thr wt wt Val309Phe wt Gly10Ala Cys12Thr wt Ural
270 A7569-19 Ser531Leu Ser315Thr wt wt Asn296His Asp94HisSer95Thr wt  Gly37Thr wt LAM
271 A7610-19 Ser531Leu Ser315Thr wt wt wt wt wt wt wt Beijing
272 A7683-19 wt wt wt wt wt wt wt wt wt Beijing
273 A7688-19 wt wt wt wt wt wt wt wt wt T 1_RUS 2
274 A7721-19 wt Ser315Thr wt wt wt wt wt wt Cys1402Thr LAM
275 A7730-19 wt wt wt wt wt wt wt wt wt LAM
276 A7731-19 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt wt Ala1401Gly B0 / W148 Beijing
277 A7733-19 wt wt wt wt wt wt wt wt wt LAM
278 A7737-19 wt wt wt wt wt wt wt wt wt Beijing
279 A7787-19 Ser531Leu Iley335Val wt wt Asn296His Asp94GlySer95Thr wt Gly10Ala wt Beijing
280 A7916-19 wt wt wt wt Val309Phe wt wt wt wt T 1_RUS 2
281 A7918-19 wt wt wt wt wt wt wt wt wt T 1
282 A8069-19 wt wt wt wt wt wt wt wt wt T 1
283 U0074-20 Ser531Leu wt wt wt Asp354Ala wt wt wt wt Beijing
284 U0113-20 wt wt wt wt wt wt wt wt wt Haarlem
285 U0118-20 wt Ser315Thr  T15A wt Gly406Ala wt wt wt wt Beijing
286 U0123-20 wt   wt wt wt wt wt wt wt Ural
287 U0263-20 Ser531Leu Ser315Thr  T15A wt Gln497Arg Ala90Val-Ser91Pro Thr539Pro wt wt Beijing
288 U0284-20 Ser531Leu Ser315Thr wt wt Gln497Arg Ala90Val-Ser91Pro Ala543Thr  Gly37Thr wt Beijing
289 U0382-20 wt wt wt wt wt wt wt wt wt LAM
290 U0444-20 Ser531Leu Ser315Thr  T15A wt Gly406Ala wt wt wt wt Beijing
291 U0562-20 Ser531Leu Ser315Thr wt wt Asp354Ala wt Ala543Thr  Gly37Thr wt Beijing
292 U0582-20 wt wt wt wt wt wt wt   wt Beijing
293 U0589-20 wt wt wt wt wt wt wt   wt Ural
294 U0591-20 Leu511Pro Ser315Thr wt wt wt His70Arg wt  Gly37Thr wt Beijing
295 U0592-20 wt Ser315Thr wt wt Asp354Ala wt wt   wt Beijing
296 U0593-20 Leu511Pro Ser315Thr wt wt wt Ala90Val-Ser91Pro Ala543Val  Gly37Thr wt Beijing
297 U0594-20 Ser531Leu wt wt wt Gln497Arg wt wt wt wt Beijing
298 U0678-20 wt wt wt wt wt wt wt wt wt T 1
299 U0731-20 wt wt wt wt wt wt wt wt wt T 1
300 U0750-20 wt wt wt wt wt wt wt wt wt LAM
301 U1262-20 Asp516Tyr wt wt wt wt wt wt wt wt LAM
302 U1356-20 wt wt wt wt wt wt wt wt wt Ural
303 U1388-20 wt Ser315Thr  T15A wt Gln497Arg wt wt wt wt Beijing
304 U1468-20 Ser531Leu Ser315Thr  T15A wt wt wt wt wt wt Beijing
305 U1596-20 wt wt wt wt wt wt wt wt wt Haarlem
306 U1740-19 wt wt wt wt wt wt wt wt wt Beijing
307 U1751-20 Leu511Pro wt wt wt Gln497Arg wt wt wt wt Beijing
308 U1761-19 Leu533Pro Ser315Thr  T15A wt wt Ala90Val-Ser91Pro wt wt Ala1401Gly Beijing
309 U1889-19 wt Ser315Arg  wt wt Gly406Ala wt wt wt wt Beijing
310 U190-20 Leu511Pro Ser315Gly    T15A wt Met306Val Asp94AlaSer95Thr  wt  Gly37Thr   Beijing
311 U192-20 Ser531Leu Ser315Arg   T15A wt Gln497Arg wt wt wt wt Beijing
312 U2115-20 Ser531Leu wt wt wt Asp354Ala wt wt wt wt Beijing
313 U2129-19  Asp516Val Ser315Thr wt wt Met306Val Pro102His  wt  Gly37Thr   LAM
314 U2152-19  Asp516Val Ser315Thr  T15A wt Gln497Arg wt wt wt wt Beijing
315 U2197-19 Ser531Leu Ser315Thr  T15A wt Met306Val wt wt wt wt Beijing
316 U2316-19 Leu511Pro Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
317 U2320-19 Ser531Leu   wt wt Gln497Arg wt wt wt wt Beijing
318 U2322-19 wt Ser315Gly   wt wt Gln497Arg wt wt wt wt Beijing
319 U2331-19 wt wt wt wt wt wt wt wt wt T 1_RUS  2
320 U2346-19 Ser531Leu Ser315Thr  T15A wt Asp354Ala wt wt wt wt Beijing
321 U2352-19 wt wt wt wt wt wt wt wt wt T 2
322 U2434-19 His526Asn Ser315Thr wt wt Asn296His wt wt Gly10Ala wt LAM
323 U2466-20 Ser531Leu Ser315Thr  T15A wt wt Ala90Val-Ser91Pro Ser486Phe  Gly37Thr wt Beijing
324 U2473-19 Ser531Leu Ser315Thr wt wt Met306Val Pro102His wt   wt B0 / W148 Beijing
325 U2510-19  Asp516Ala wt wt wt  Gly406Asp Ala90Gly-Ser91Pro wt Cys14Thr wt B0 / W148 Beijing
326 U2607-19 Asp516Tyr wt wt wt wt wt wt wt wt Beijing
327 U2639-19 wt Ser315Thr wt wt Val309Phe wt wt Cys12Thr wt LAM 9
328 U2644-19 wt wt wt wt wt wt wt wt wt LAM
329 U2651-19 Leu533Pro Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
330 U2663-19 Ser531Leu   wt wt Met306Val wt wt wt wt Haarlem
331 U2664-19 Ser531Leu Ser315Thr wt wt wt wt wt wt wt B0 / W148 Beijing
332 U2672-19 Ser531Leu Ser315Thr wt wt Gly406Ala Asp94AlaSer95Thr wt Gly10Ala wt B0 / W148 Beijing
333 U2680-20 Ser531Leu Ser315Thr   wt Asp354Ala Asp94AlaSer95Thr wt wt wt Beijing
334 U2704-19  Asp516Ala Ser315Thr   wt Asp354Ala Asp94AlaSer95Thr wt wt wt Beijing
335 U2708-19 wt Ser315Thr wt wt Met306Leu wt wt  Gly37Thr wt LAM
336 U2714-19 wt Ser315Thr  T15A wt Met306Leu wt wt wt wt LAM
337 U2803-19 wt wt wt wt wt wt wt wt wt Beijing
338 U2835-19 Ser531Leu Ser315Thr wt wt Asp354Ala wt wt wt wt Beijing
339 U2845-19 wt wt wt wt wt wt wt wt wt Beijing
340 U2876-19  Asp516Val Ser315Thr wt wt Met306Leu wt wt Cys12Thr wt T 1
341 U3048-20 wt wt wt wt wt wt wt wt wt T 1
342 U3059-19 wt Ser315Thr wt wt wt wt wt wt wt Beijing
343 U3075-20 wt wt wt wt wt wt wt wt wt Ural
344 U3381-19 Ser531Leu Ser315Thr wt wt Met306Val wt wt  Gly37Thr wt LAM
345 U3435-19 Ser531Leu Ser315Thr wt wt Met306Val wt wt wt wt B0 / W148 Beijing
346 U3480-19 wt wt wt wt Gln497Arg wt wt wt wt Beijing
347 U3483-19 wt Ser315Thr wt wt wt wt wt wt wt LAM
348 U3492-19  Asp516Ala Ser315Thr wt wt Met306Val wt wt wt wt Beijing
349 U3532-19 Ser531Leu Ser315Thr wt wt Met306Val wt wt wt wt B0 / W148 Beijing
350 U3564-19 Ser531Leu Ser315Thr wt wt Asp354Ala Asp94AlaSer95Thr wt  Gly37Thr wt Beijing
351 U3574-19 Ser531Leu Trp328Cys wt wt Gln497Arg wt wt wt wt Beijing
352 U4144-19 wt wt wt wt wt wt Thr539 Ile wt wt Haarlem
353 U4157-19 Ser531Leu Ser315Thr wt wt Met306Leu wt wt wt wt Ural
354 U4158-19 wt wt wt wt wt wt wt wt wt T 4
355 U4171-19 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
356 U4271-19  Asp516Ala Ser315Thr wt wt Asp354Ala wt wt wt wt Beijing
357 U4543-20 Ser531Leu wt wt wt wt wt wt wt wt Beijing
358 U4611-20 wt Ser315Thr  T15A wt wt wt wt wt wt Beijing
359 U4859-20 Ser531Leu Ser315Thr wt wt Met306Val Asp94AlaSer95Thr wt Gly10Ala wt B0 / W148 Beijing
360 U5289-19 Ser531Leu Ser315Thr  T15A wt Asp354Ala wt Asp500Asn  Gly37Thr wt Beijing
361 U5290-19 Ser531Leu Ser315Thr wt wt Met306Val wt wt wt wt Beijing
362 U5291-19 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
363 U5302-19 Leu511Pro   wt wt Asp354Ala wt wt wt wt Beijing
364 U5337-19 Ser531Leu Ser315Thr wt wt Met306Val Asp94HisSer95Thr wt Gly10Ala wt LAM
365 U5493-19 wt wt wt wt wt wt wt Cys12Thr wt Ural
366 U5513-19 wt wt wt wt wt wt wt wt wt T 1
367 U5564-19 wt wt wt wt wt wt wt wt wt X 1
368 U5621-19 Ser531Leu Ser315Thr wt wt Met306Val wt wt wt wt Beijing
369 U5637-19 wt Ser315Thr wt wt wt wt wt Gly10Ala wt X 1
370 U5713-19 Ser531Leu wt wt wt Met306Leu wt   wt wt B0 / W148 Beijing
371 U5731-19 Ser531Leu Ser315Thr wt wt Asp354Ala wt   wt wt Beijing
372 U5737-19 Leu511Pro Ser315Thr wt wt Met306Val wt   wt wt Beijing
373 U5809-19 Ser531Leu Ser315Thr wt wt Gln497Arg wt Gly10Ala wt wt Beijing
374 U5839-19 wt wt wt wt wt wt wt wt wt Beijing
375 U5850-19  Asp516Ala Ser315Thr  T15A wt wt wt wt  Gly37Thr wt Beijing
376 U5897-19 wt   wt wt wt wt wt wt wt Ural
377 U6025-19 wt wt wt wt wt wt wt wt wt LAM
378 U6031-19 wt Ser315Thr wt wt Met306Leu wt wt wt wt LAM
379 U6048-19 wt wt wt wt wt wt wt wt wt LAM
380 U6142-19 Ser531Leu Ser315Thr wt wt Met306Val wt wt wt wt Beijing
381 U6193-19 wt wt wt wt wt wt wt wt wt T 1
382 U6202-19 Leu533Pro Ser315Thr wt wt Asp354Ala wt wt wt wt B0 / W148 Beijing
383 U6275-19 wt wt wt wt Asp354Ala wt wt wt wt Beijing
384 U6286-19 Ser531Leu wt wt wt  Gly406Asp wt wt wt Ala1401Gly B0 / W148 Beijing
385 U6347-19 His526Asn wt wt wt wt wt   wt wt LAM
386 U6364-19 Ser531Leu Ser315Thr wt wt wt Ala90Val-Ser91Pro wt  Gly37Thr wt Beijing
387 U6371-19 wt wt wt wt wt wt wt wt wt LAM
388 U6372-19 His526Pro wt wt wt wt wt wt wt wt LAM
389 U6463-19 wt Trp328Cys wt wt wt wt wt wt wt Beijing
390 U6587-19 wt wt wt wt wt wt wt wt wt T 3
391 U6696-19 wt wt wt wt wt wt wt wt wt LAM
392 U6703-19 wt wt  T15A wt wt wt wt wt wt LAM
393 U6767-19 wt wt wt wt Met306Leu wt wt wt Ala1401Gly B0 / W148 Beijing
394 U6927-20 Ser531Leu Ser315Thr  T15A wt Met306Val wt wt wt wt Beijing
395 U7056-19 Ser531Leu Ser315Thr wt wt Asp354Ala wt wt wt wt Beijing
396 U7091-19 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
397 U7192-19 wt Ser315Thr wt wt Met306Val wt wt wt wt Beijing
398 U7295-19 wt Ser531Leu wt wt Met306Val wt wt wt wt Beijing
399 U7305-19 wt wt wt wt wt wt wt wt wt T 1
400 U7309-19 wt wt wt wt Gln497Lys wt wt wt wt T 3
401 U7328-19 Ser531Leu Ser315Thr wt wt Asp354Ala wt wt wt wt B0 / W148 Beijing
402 U7333-19 wt wt wt wt wt wt wt wt wt LAM
403 U7537-19 Ser531Leu Ser315Thr wt wt  Gly406Asp wt wt wt wt B0 / W148 Beijing
404 U7592-19 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
405 U7609-19 Ser531Leu Ser315Thr wt wt Asp354Ala wt wt wt wt Beijing
406 U7707-19 Asp516Tyr Ser315Thr wt wt Asp354Ala wt wt Cys12Thr wt Ural
407 U7721-19 wt wt  T15A wt wt wt wt wt wt LAM
408 U7732-19 wt wt wt wt wt wt wt wt wt Ural
409 U7789-19 Ser531Leu wt wt wt Met306Val wt wt wt wt B0 / W148 Beijing
410 U7865-19 Ser531Leu Iley335Val wt wt wt wt wt wt wt Beijing
411 U7870-19 Ser531Leu Ser315Thr wt wt Met306Leu wt wt Cys14Thr wt B0 / W148 Beijing
412 U7879-19 wt Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
413 U7882-19  Asp516Ala Ser315Thr wt wt Asp354Ala wt wt Gly10Ala wt Beijing
414 U7912-19 Ser531Leu Ser315Thr wt wt Met306Leu wt wt wt wt B0 / W148 Beijing
415 U7913-19 Ser531Leu Ser315Thr wt wt Asn296His wt wt wt wt Beijing
416 U7914-19 Ser531Leu Ser315Thr wt wt Met306Val Asp94GlySer95Thr wt Gly10Ala wt Beijing
417 U7917-19 wt wt wt wt wt wt wt wt wt Beijing
418 U7919-19 wt wt wt wt wt wt wt wt wt Beijing
419 U7920-19 Ser531Leu Ser315Thr wt wt Met306Val Asp94GlySer95Thr wt Gly10Ala wt Beijing
420 U7921-19 Ser531Leu Iley335Val wt wt Asn296His wt wt wt wt Beijing
421 U7922-19 Ser531Leu Ser315Thr wt wt Met306Val Asp94GlySer95Thr wt  Gly37Thr wt Beijing
422 U7923-19 wt wt wt wt Asn296His wt wt wt wt B0 / W148 Beijing
423 U7924-19 Ser531Leu Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
424 U7929-19 wt wt wt wt Asn296His wt wt wt wt B0 / W148 Beijing
425 U7936-19 Ser531Leu Ser315Thr wt wt Met306Leu Asp94TyrSer95Thr wt  Gly37Thr wt LAM
426 U8056-19 Ser531Leu wt wt wt wt wt wt wt wt Beijing
427 U8133-19 Leu533Pro Ser315Thr wt wt Gly406Ala wt wt wt wt B0 / W148 Beijing
428 U8571-19 Ser531Leu Ser315Thr wt wt  Gly406Ser Ala90Val-Ser91Pro,
Asp94AsnSer95Thr
Ala543Val Gly10Ala wt B0 / W148 Beijing
429 U8739-19 Ser531Leu wt wt wt Met306Leu wt wt wt wt B0 / W148 Beijing
430 U9231-19 wt wt wt wt wt wt wt wt wt Beijing
431 U9407-19 Ser531Leu Ser315Thr wt wt Met306Val wt wt wt wt Beijing
432 U9797-19 Ser531Leu Ser315Thr wt wt Met306Val Asp94GlySer95Thr wt  Gly37Thr wt Beijing
433 U9928-19 Ser531Leu Ser315Thr wt wt Asn296His wt wt wt wt Beijing